2024
Observational study protocol for an arrhythmia notification feature
Kumar S, Weinstein J, Melchinger H, Smith A, Capodilupo E, Akar J, Garg K, O’Connor K, Staunton M, Martin M, Akhlaghi N, Edeh O, Perez S, Lee V, Lee K, Wilson F. Observational study protocol for an arrhythmia notification feature. BMJ Open 2024, 14: e075110. PMID: 38830741, PMCID: PMC11149124, DOI: 10.1136/bmjopen-2023-075110.Peer-Reviewed Original ResearchConceptsAtrial fibrillationInstitution of appropriate treatmentGold standardClinical research journalsAssessment of risk factorsObservational study protocolRecruited participantsEthics BoardGeneral populationDiagnosed AFHealthy controlsPrimary outcomeAppropriate treatmentStudy protocolRisk factorsConsent documentsWHOOP strapParticipantsArrhythmiasDetect AFWearable technology
2023
Clinical presentation of group B Streptococcus-infected diabetic foot ulcers
Waldman O, Dexter B, Sulovari A, Oh I. Clinical presentation of group B Streptococcus-infected diabetic foot ulcers. Journal Of Wound Care 2023, 32: s19-s25. PMID: 37405964, DOI: 10.12968/jowc.2023.32.sup7.s19.Peer-Reviewed Original ResearchConceptsDiabetic foot ulcersFoot ulcersBlack patientsRecurrent infectionsElevated hemoglobin A1cIntra-operative culturesHemoglobin A1c levelsInitial laboratory valuesSoft tissue infectionsDFU infectionsDFU patientsInitial surgeryOrthopaedic FootAggressive treatmentClinical characteristicsGBS infectionA1c levelsHemoglobin A1cTissue infectionsClinical outcomesClinical presentationInfected boneAppropriate treatmentGroup BLaboratory valuesPrecipitated Opioid Withdrawal Treated With Ketamine in a Hospitalized Patient: A Case Report
Christian N, Butner J, Evarts M, Weimer M. Precipitated Opioid Withdrawal Treated With Ketamine in a Hospitalized Patient: A Case Report. Journal Of Addiction Medicine 2023, 17: 488-490. PMID: 37579118, DOI: 10.1097/adm.0000000000001151.Peer-Reviewed Case Reports and Technical NotesConceptsClinical Opiate Withdrawal Scale (COWS) scoresOpioid use disorderKetamine infusionOpioid withdrawalCase reportUse disordersScale scoreSevere opioid use disorderFull opioid agonistsHours of admissionEmergency department settingFirst case reportInpatient hospital settingLife-saving medicationsReceptor-mediated signalingLack of evidenceMale patientsFentanyl useOpioid agonistsEmergency departmentComplete resolutionDepartment settingClinical dilemmaAppropriate treatmentHospital settingUltrasound Evaluation of Chronic Venous Insufficiency
Zalaquett E, Gunabushanam G, Vallejos A, Dahiya N. Ultrasound Evaluation of Chronic Venous Insufficiency. Ultrasound Quarterly 2023, 39: 2-9. PMID: 36651650, DOI: 10.1097/ruq.0000000000000634.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsChronic venous insufficiencyVenous insufficiencyVenous systemLower extremity venous systemDeep venous systemExtent of refluxPreferred imaging modalityMild painValvular incompetenceVenous ulcersClinical presentationUltrasound evaluationVaricose veinsAppropriate treatmentRadiation-free mannerCommon conditionDoppler ultrasoundImaging modalitiesScanning protocolInsufficiencyRelevant findingsPainEdemaUlcersActionable reports
2022
Diagnosis and management of immune checkpoint inhibitor-associated acute kidney injury
Sprangers B, Leaf DE, Porta C, Soler MJ, Perazella MA. Diagnosis and management of immune checkpoint inhibitor-associated acute kidney injury. Nature Reviews Nephrology 2022, 18: 794-805. PMID: 36168055, DOI: 10.1038/s41581-022-00630-8.Peer-Reviewed Original ResearchConceptsImmune checkpoint inhibitorsAcute kidney injuryKidney injuryKidney biopsyAcute tubulo-interstitial nephritisImmune-related adverse eventsConcomitant anticancer therapyTubulo-interstitial nephritisEffector T cellsEvaluation of patientsLoss of toleranceCheckpoint inhibitorsPartial remissionPermanent discontinuationAdverse eventsMost patientsAppropriate treatmentEarly initiationT cellsClinical practiceFavorable responsePatientsAccurate diagnosisCancer treatmentAnticancer therapyPredicting resistance to fluoroquinolones among patients with rifampicin-resistant tuberculosis using machine learning methods
You S, Chitwood MH, Gunasekera KS, Crudu V, Codreanu A, Ciobanu N, Furin J, Cohen T, Warren JL, Yaesoubi R. Predicting resistance to fluoroquinolones among patients with rifampicin-resistant tuberculosis using machine learning methods. PLOS Digital Health 2022, 1: e0000059. PMID: 36177394, PMCID: PMC9518704, DOI: 10.1371/journal.pdig.0000059.Peer-Reviewed Original ResearchDrug susceptibility testXpert MTB/RIFMachine learning-based modelsLearning-based modelsMachine learning methodsRifampicin-resistant tuberculosisTime of diagnosisRifampin-resistant tuberculosisMTB/RIFNeural network modelLearning methodsNetwork modelMulti-drug resistant tuberculosisNational TB surveillanceDrug-resistant tuberculosisOptimism-corrected areaSelection of antibioticsAnti-TB agentsDistrict-level prevalenceLow-resource settingsPatient characteristicsResistant tuberculosisTB surveillanceAppropriate treatmentDST resultsDoes Being Diagnosed As Anemic in Early Pregnancy Have an Impact on the Household Expenditure for Food? Evidence From a Maternal Cohort in Rural Sri Lanka
Gunarathne S, Amarasinghe G, Agampodi T, Wickramasinghe N, Mendis V, Prasanna I, Agampodi S. Does Being Diagnosed As Anemic in Early Pregnancy Have an Impact on the Household Expenditure for Food? Evidence From a Maternal Cohort in Rural Sri Lanka. Current Developments In Nutrition 2022, 6: 654. PMCID: PMC9193294, DOI: 10.1093/cdn/nzac061.038.Peer-Reviewed Original ResearchNon-anaemic womenEarly pregnancyPregnant womenRural Sri LankaFirst trimester pregnant womenPublic health midwivesHousehold food expenditureThird of pregnanciesAnemic pregnant womenMann-Whitney U testDiagnosis of anemiaMonthly household incomeLifestyle modificationHemoglobin levelsPregnancy cohortThird trimesterMean ageModerate anemiaMaternal cohortAppropriate treatmentHousehold economic statusNutritional educationSelf-administrated questionnairePregnancyAnemia
2021
Outcomes-Driven Clinical Phenotyping in Cardiogenic Shock using a Mixture of Experts
Hurley N, Berkowitz A, Masoudi F, Ross J, Desai N, Shah N, Dhruva S, Mortazavi B. Outcomes-Driven Clinical Phenotyping in Cardiogenic Shock using a Mixture of Experts. 2021, 00: 1-4. DOI: 10.1109/bhi50953.2021.9508568.Peer-Reviewed Original ResearchFever, pancytopenia, and elevated D-dimer in a 95‐year‐old woman with ehrlichiosis: a case report
Radcliffe C, Tsay C, Glerum K, Liao J, Goshua G, Kerins G. Fever, pancytopenia, and elevated D-dimer in a 95‐year‐old woman with ehrlichiosis: a case report. BMC Geriatrics 2021, 21: 178. PMID: 33711942, PMCID: PMC7953191, DOI: 10.1186/s12877-021-02129-6.Peer-Reviewed Original ResearchConceptsD-dimerPulmonary emboliSevere coronavirus disease 2019Hospital day 7Computed tomography angiogramSignificant clinical findingsPeripheral blood smearCoronavirus disease 2019Concurrent ehrlichiosisDoxycycline monotherapyHospital stayHigh feverSymptomatic improvementTomography angiogramCase presentationWeClinical findingsLarge academic institutionCase reportArteriovenous malformationsAppropriate treatmentDifferential diagnosisUnexpected presentationDisease 2019Hematological malignanciesDay 7Adrenal Tumors
Model L, Caty M, Christison-Lagay E. Adrenal Tumors. 2021, 1073-1088. DOI: 10.1007/978-3-662-43559-5_157.ChaptersManagement of Refractory Ascites Due to Portal Hypertension: Current Status.
Madoff DC, Cornman-Homonoff J, Fortune BE, Gaba RC, Lipnik AJ, Yarmohammadi H, Ray CE. Management of Refractory Ascites Due to Portal Hypertension: Current Status. Radiology 2021, 298: 493-504. PMID: 33497318, DOI: 10.1148/radiol.2021201960.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsRefractory ascitesPortal hypertensionTransjugular intrahepatic portosystemic shuntLarge-volume paracentesesCirrhotic portal hypertensionAvailable therapeutic optionsIntrahepatic portosystemic shuntStepwise management approachMost patientsMedical managementPoor prognosisPortosystemic shuntTherapeutic optionsTreatment optionsMultiple therapiesPatient outcomesAppropriate treatmentClinical experienceDrainage deviceSpecific patientAscitesHypertensionPatientsParacentesesPrognosis
2020
Adrenal Tumors
Model L, Caty M, Christison-Lagay E. Adrenal Tumors. 2020, 1-16. DOI: 10.1007/978-3-642-38482-0_157-1.Peer-Reviewed Original ResearchUrinary Tract Infection USA
Arlen A, Cooper C. Urinary Tract Infection USA. 2020, 1-5. DOI: 10.1007/978-3-030-24730-0_1.Peer-Reviewed Original Research
2019
Climate change and quality of health care: evidence from extreme heat
Si Y, Zhou Z, Su M, Chen X. Climate change and quality of health care: evidence from extreme heat. The Lancet 2019, 394: s94. DOI: 10.1016/s0140-6736(19)32430-4.Peer-Reviewed Original ResearchCommunity health centersClinical checklistHealth centersHealth careNational InstituteQuality of careHealth service deliveryNecessary health servicesXi'an Jiaotong UniversityAccuracy of diagnosisPhysician adherencePhysical examinationPrimary careAppropriate treatmentCorrect diagnosisPatientsHealth servicesPhysiciansCareMean numberAdherenceMedical boardsImproved qualityStandardised patientsChecklist itemsEstimating the benefits of therapy for early-stage breast cancer: the St. Gallen International Consensus Guidelines for the primary therapy of early breast cancer 2019
Burstein H, Curigliano G, Loibl S, Dubsky P, Gnant M, Poortmans P, Colleoni M, Denkert C, Piccart-Gebhart M, Regan M, Senn H, Winer E, Thurlimann B, 2019 M. Estimating the benefits of therapy for early-stage breast cancer: the St. Gallen International Consensus Guidelines for the primary therapy of early breast cancer 2019. Annals Of Oncology 2019, 30: 1541-1557. PMID: 31373601, DOI: 10.1093/annonc/mdz235.Peer-Reviewed Original ResearchConceptsEarly-stage breast cancerBreast cancerBreast cancer histologyClinical benefitCancer histologySt. Gallen Consensus ConferenceEarly breast cancerInternational consensus guidelinesBenefits of therapyBreast cancer recurrenceSubstantial new evidenceMagnitude of benefitAdjuvant therapyLack of evidencePrimary therapyOverall survivalSystemic therapyHealthy womenConsensus guidelinesCancer recurrenceAppropriate treatmentClinical studiesIndividual patientsPatient participationConsensus conferenceLong-term Follow-up of Severe Eosinophilic Hepatitis: A Rare Presentation of Hypereosinophilic Syndrome
Awadie H, Khoury J, Zohar Y, Yaccob A, Veitsman E, Saadi T. Long-term Follow-up of Severe Eosinophilic Hepatitis: A Rare Presentation of Hypereosinophilic Syndrome. Rambam Maimonides Medical Journal 2019, 10: e0020. PMID: 31335311, PMCID: PMC6649775, DOI: 10.5041/rmmj.10373.Peer-Reviewed Original ResearchHypereosinophilic syndromeIdiopathic hypereosinophilic syndromeLiver involvementLong-term Follow-upIsolated liver involvementSolid organ involvementRare systemic diseaseEnd-organ damageIntensive immunosuppressive treatmentAdvanced liver failureHigher eosinophil countsEosinophilic hepatitisImmunosuppressive treatmentChronic hepatitisLiver dysfunctionOrgan involvementLiver biopsyLiver failureEosinophil countOrgan damageRare presentationSystemic diseaseFollow-upAppropriate treatmentLow doseFirst data on antimicrobial susceptibility patterns of Moraxella catarrhalis isolates in Lebanon
Hamze M, Osman M, Mallat H, Achkar M. First data on antimicrobial susceptibility patterns of Moraxella catarrhalis isolates in Lebanon. The International Arabic Journal Of Antimicrobial Agents 2019, 9 DOI: 10.3823/833.Peer-Reviewed Original ResearchAntimicrobial susceptibility patternsMoraxella catarrhalisSusceptibility patternsM. catarrhalisM. catarrhalis strainsAntibiotic susceptibility ratesEffective empirical treatmentThroats of patientsAntimicrobial susceptibility profilesEmergence of resistanceAntimicrobial susceptibility testingMajority of antibioticsReliable diagnostic toolNini HospitalTrimethoprim-sulfamethoxazoleAppropriate treatmentEmpirical treatmentSusceptibility ratesAntibiotic susceptibilityClinical specimensCatarrhalisPercent susceptibilityClinical settingSusceptibility testingSusceptibility profilesCutaneous Basal Cell Carcinoma with Bone Metastases: An Orthopaedic Case Report
Fram BR, Strony J, Jagannathan G, Brown SA. Cutaneous Basal Cell Carcinoma with Bone Metastases: An Orthopaedic Case Report. Case Reports In Orthopedics 2019, 2019: 1628980. PMID: 31341689, PMCID: PMC6612392, DOI: 10.1155/2019/1628980.Peer-Reviewed Original ResearchBasal cell carcinomaMetastatic BCCCell carcinomaHistory of BCCMetastatic basal cell carcinomaCutaneous basal cell carcinomaRate of metastasisCommon skin cancerBone metastasesOsseous metastasesCase reportOrthopedic oncologistAppropriate treatmentCorrect diagnosisAge 50Orthopaedic literatureSkin cancerUnknown originCarcinomaMetastasisPatientsSkin pigmentationLight skin pigmentationFirst reportReportIncidence of pancreatitis with the use of immune checkpoint inhibitors (ICI) in advanced cancers: A systematic review and meta-analysis
George J, Bajaj D, Sankaramangalam K, Yoo JW, Joshi NS, Gettinger S, Price C, Farrell JJ. Incidence of pancreatitis with the use of immune checkpoint inhibitors (ICI) in advanced cancers: A systematic review and meta-analysis. Pancreatology 2019, 19: 587-594. PMID: 31076344, DOI: 10.1016/j.pan.2019.04.015.Peer-Reviewed Original ResearchConceptsImmune checkpoint inhibitorsIncidence of pancreatitisImmune side effectsPD-1 inhibitorsLipase elevationCheckpoint inhibitorsClinical trialsSide effectsSystematic reviewCTLA-4 agentsGrade 2 pancreatitisCTLA-4 inhibitorsLong-term complicationsNon-melanoma cancersICI combinationsICI useTerm complicationsAdvanced cancerTrue incidenceCTLA-4Appropriate treatmentPancreatitisSolid tumorsTumor typesPatients
2018
Patterns of Opioid Prescribing and Predictors of Chronic Opioid Use in an Industrial Cohort, 2003 to 2013
Pensa MA, Galusha DH, Cantley LF. Patterns of Opioid Prescribing and Predictors of Chronic Opioid Use in an Industrial Cohort, 2003 to 2013. Journal Of Occupational And Environmental Medicine 2018, 60: 457-461. PMID: 29135839, PMCID: PMC5943140, DOI: 10.1097/jom.0000000000001231.Peer-Reviewed Original ResearchConceptsChronic opioid useOpioid prescribingOpioid useChronic opioid prescribingOpioid prescription patternsLow back painOccupational health professionalsWork-related injuriesHealth care claimsCross-sectional analysisPrescription patternsBack painChronic prescriptionOpioid epidemicAppropriate treatmentWhite raceCare claimsHealth professionalsIndustrial cohortOlder agePrescribingStrongest predictorPredictorsProportion of workersAdditional predictors
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