Insulin clearance at randomisation and in response to treatment in youth with type 2 diabetes: a secondary analysis of the TODAY randomised clinical trial
Nadeau K, Arslanian S, Bacha F, Caprio S, Chao L, Farrell R, Hughan K, Rayas M, Tung M, Cross K, El ghormli L. Insulin clearance at randomisation and in response to treatment in youth with type 2 diabetes: a secondary analysis of the TODAY randomised clinical trial. Diabetologia 2024, 68: 676-687. PMID: 39706874, DOI: 10.1007/s00125-024-06327-w.Peer-Reviewed Original ResearchConceptsYouth-onset type 2 diabetesType 2 diabetesBeta cell functionRandomised clinical trialsVisceral adipose tissueMarkers of adiposityInsulin sensitivityInsulin clearanceSubcutaneous adipose tissueCell functionClinical trialsResponse to rosiglitazone treatmentDual-energy X-ray absorptiometryPersistently elevated blood glucose levelsMarkers of insulin sensitivityFasting blood testsX-ray absorptiometryFasting C-peptideNon-Hispanic black raceAdipose tissueResponse to treatmentCompensatory response to changesElevated blood glucose levelsNational Institute of DiabetesSecondary analysis
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply