Modeling Endothelial Cell-Targeted Polymeric Nanoparticle Delivery in Renal Glomeruli
Richfield O, Tolbert-Schwartz E, Saltzman W. Modeling Endothelial Cell-Targeted Polymeric Nanoparticle Delivery in Renal Glomeruli. 2024 DOI: 10.70534/zjdh1719.Peer-Reviewed Original ResearchGlomerular diseaseNanoparticle deliveryGlomerular capillariesGlomerular endotheliumRenal autoregulationDesign of novel therapiesReduced renal massCell-targeting antibodiesChronic kidney diseaseDelivery of nanoparticlesCapillary networkNormothermic machine perfusionFiltration of plasmaRenal massesEffective therapeutic delivery systemsNovel therapiesGlomerular capillary wallGlomerular hemodynamicsRat glomeruliKidney diseaseTherapeutic delivery systemsGlomerular capillary networkShear stressHematocrit changesEndothelium
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