Systemic Inflammation Induced by microRNAs: Endometriosis-Derived Alterations in Circulating microRNA 125b-5p and Let-7b-5p Regulate Macrophage Cytokine Production
Nematian SE, Mamillapalli R, Kadakia TS, Zolbin M, Moustafa S, Taylor HS. Systemic Inflammation Induced by microRNAs: Endometriosis-Derived Alterations in Circulating microRNA 125b-5p and Let-7b-5p Regulate Macrophage Cytokine Production. The Journal Of Clinical Endocrinology & Metabolism 2017, 103: 64-74. PMID: 29040578, DOI: 10.1210/jc.2017-01199.Peer-Reviewed Original ResearchConceptsSera of patientsMacrophage cytokine productionIL-1βIL-6Cytokine productionIL-8Let-7bIL-1β levelsCytokine protein levelsU937 macrophage cell lineCase-control studyTumor necrosis factorLet-7b inhibitorReal-time polymerase chain reactionEnzyme-linked immunosorbentQuantitative real-time polymerase chain reactionMessenger RNA changesSystemic inflammationAberrant inflammationInflammatory cytokinesProinflammatory cytokinesLevels of microRNAsUniversity HospitalPolymerase chain reactionMacrophage cell line
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