Emily Olfson, MD, PhD
Cards
Appointments
Additional Titles
Solnit Integrated Program, Yale Child Study Center
Contact Info
Child Study Center
230 S Frontage Rd
New Haven, Connecticut 06519-1124
United States
Appointments
Additional Titles
Solnit Integrated Program, Yale Child Study Center
Contact Info
Child Study Center
230 S Frontage Rd
New Haven, Connecticut 06519-1124
United States
Appointments
Additional Titles
Solnit Integrated Program, Yale Child Study Center
Contact Info
Child Study Center
230 S Frontage Rd
New Haven, Connecticut 06519-1124
United States
About
Titles
Assistant Professor in the Child Study Center
Solnit Integrated Program, Yale Child Study Center
Biography
Emily Olfson is a physician-scientist whose research focuses on the genetics of childhood-onset psychiatric conditions. She received her MD-PhD from Washington University in St. Louis where her dissertation in Human and Statistical Genetics focused on the genetics of smoking and alcoholism in the laboratory of Dr. Laura Bierut. She then completed residency and fellowship training in child, adolescent, and adult psychiatry in the Yale Solnit Integrated Program and additional research training in the laboratory of Dr. Thomas Fernandez. Current projects in the Olfson laboratory focus on translational neurogenomic investigations of trichotillomania, excoriation disorder, attention-deficit/hyperactivity disorder, chronic tic disorders, obsessive-compulsive disorder, misophonia, and childhood anxiety disorders. Dr. Olfson works clinically with adults and children in the Tic and OCD Program in the Yale Child Study Center. She has received research support from the National Institutes of Health, the Tourette Association of America, The Hartwell Foundation, Misophonia Research Fund, International OCD Foundation, Klingenstein Third Generation Foundation, American Academy of Child and Adolescent Psychiatry, and the Alan B. Slifka Foundation through the Riva Ariella Ritvo endowment.
Appointments
Child Study Center
Assistant ProfessorPrimary
Other Departments & Organizations
- Albert J. Solnit Integrated Training Program
- Child Study Center
- Fernandez Lab
- Interdepartmental Neuroscience Program
- Janeway Society
- Molecular Medicine, Pharmacology, and Physiology
- Neuroscience Research Training Program (NRTP)
- Neuroscience Track
- Program in Neurodevelopment and Regeneration
- Program in Translational Biomedicine (PTB)
- Wu Tsai Institute
- Yale Combined Program in the Biological and Biomedical Sciences (BBS)
- Yale Medicine
Education & Training
- Fellowship
- Yale School of Medicine, Child Study Center (2022)
- Residency
- Yale School of Medicine, Psychiatry (2021)
- PhD
- Washington University School of Medicine in St Louis, Human and Statistical Genetics (2016)
- MD
- Washington University School of Medicine in St Louis, Human and Statistical Genetics (2016)
- BA
- Oberlin College, Biology and Mathematics
Research
Overview
Medical Research Interests
ORCID
0000-0002-6438-0079
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Michael Bloch, MD, MS
Thomas Fernandez, MD
Abha Gupta, MD, PhD
Catherine Sullivan
Ellen J. Hoffman, MD, PhD
Sarah Barbara Abdallah, MD
Trichotillomania
Genomics
Obsessive-Compulsive Disorder
Genetics
Anxiety Disorders
Publications
2025
Investigating the familiality of trichotillomania and excoriation disorder.
Chen D, Farhat LC, Lebowitz ER, Silverman WK, Bloch MH, Fernandez TV, Olfson E. Investigating the familiality of trichotillomania and excoriation disorder. Psychiatry Res 2025, 350: 116560. PMID: 40449230, DOI: 10.1016/j.psychres.2025.116560.Peer-Reviewed Original ResearchCharacterizing Rare DNA Copy-Number Variants in Pediatric Obsessive-Compulsive Disorder.
Abdallah SB, Olfson E, Cappi C, Greenspun S, Zai G, Rosário MC, Willsey AJ, Shavitt RG, Miguel EC, Kennedy JL, Richter MA, Fernandez TV. Characterizing Rare DNA Copy-Number Variants in Pediatric Obsessive-Compulsive Disorder. J Am Acad Child Adolesc Psychiatry 2025 PMID: 40122455, DOI: 10.1016/j.jaac.2025.03.014.Peer-Reviewed Original Research
2024
Chapter 52 Obsessive–compulsive disorder
Abdallah S, Olfson E, Fernandez T. Chapter 52 Obsessive–compulsive disorder. Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease, Volume 2, Seventh Edition 2024, 937-950ChaptersRare de novo damaging DNA variants are enriched in attention-deficit/hyperactivity disorder and implicate risk genes
Olfson E, Farhat L, Liu W, Vitulano L, Zai G, Lima M, Parent J, Polanczyk G, Cappi C, Kennedy J, Fernandez T. Rare de novo damaging DNA variants are enriched in attention-deficit/hyperactivity disorder and implicate risk genes. Nature Communications 2024, 15: 5870. PMID: 38997333, PMCID: PMC11245598, DOI: 10.1038/s41467-024-50247-7.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsDNA sequencesRisk genesHigh-confidence risk genesWhole-exome DNA sequencingSequencing of familiesIdentified de novoLysine demethylase 5BDNA variantsTrio cohortBiological pathwaysGenesSequencing cohortGenetic factorsChildhood neurodevelopmental disordersAttention-deficit/hyperactivity disorderSequenceVariantsADHD riskNeurodevelopmental disordersKDM5BDNAMutationsFamilyLysineDiscoveryThe genetics of trichotillomania and excoriation disorder: A systematic review
Reid M, Lin A, Farhat L, Fernandez T, Olfson E. The genetics of trichotillomania and excoriation disorder: A systematic review. Comprehensive Psychiatry 2024, 133: 152506. PMID: 38833896, PMCID: PMC11513794, DOI: 10.1016/j.comppsych.2024.152506.Peer-Reviewed Original ResearchCitationsAltmetricConceptsSystematic reviewGenome-wide researchGenome-wide associationDNA sequencing studiesDiscovery of risk genesWeb of ScienceGenetic factorsObsessive-compulsive disorderGenetic epidemiologyGenetic risk factorsSequencing studiesRisk genesGeneral populationMolecular geneticsExcoriation disorderRisk factorsGeneticsFirst-line medicationPsychiatric disordersObsessive-compulsive related disordersObsessive-compulsive disorder spectrumBody-focused repetitive behaviorsDevelopment of trichotillomaniaPsycINFOGenome
2023
Primary complex motor stereotypies are associated with de novo damaging DNA coding mutations that identify KDM5B as a risk gene
Fernandez T, Williams Z, Kline T, Rajendran S, Augustine F, Wright N, Sullivan C, Olfson E, Abdallah S, Liu W, Hoffman E, Gupta A, Singer H. Primary complex motor stereotypies are associated with de novo damaging DNA coding mutations that identify KDM5B as a risk gene. PLOS ONE 2023, 18: e0291978. PMID: 37788244, PMCID: PMC10547198, DOI: 10.1371/journal.pone.0291978.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsRisk genesDe novo damaging variantsGene expression patternsWhole-exome DNA sequencingMid-fetal developmentAdditional risk genesHigh-confidence risk genesParent-child triosGene OntologyCell signalingExpression patternsCalcium ion transportFunctional convergenceCell cycleDamaging variantsGenesDNA sequencingDe novoASD probandsGenetic etiologyBiological mechanismsSequencingDNANetwork analysisIon transport25.4 Pharmacologic Interventions for Trichotillomania and Excoriation Disorder
Bloch M, Farhat L, Olfson E. 25.4 Pharmacologic Interventions for Trichotillomania and Excoriation Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2023, 62: s363. DOI: 10.1016/j.jaac.2023.07.760.Peer-Reviewed Original ResearchPediatric Body-Focused Repetitive Behaviors: A Research Update on Clinical Characteristics and Treatment Strategies
Olfson E, Piacentini J. Pediatric Body-Focused Repetitive Behaviors: A Research Update on Clinical Characteristics and Treatment Strategies. Journal Of The American Academy Of Child & Adolescent Psychiatry 2023, 62: s362. DOI: 10.1016/j.jaac.2023.07.756.Peer-Reviewed Original Research25.1 Prevalence and Clinical Characteristics of Trichotillomania and Excoriation Disorder
Farhat L, Bloch M, Olfson E. 25.1 Prevalence and Clinical Characteristics of Trichotillomania and Excoriation Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2023, 62: s362. DOI: 10.1016/j.jaac.2023.07.757.Peer-Reviewed Original ResearchPrevalence and gender distribution of excoriation (skin-picking) disorder: A systematic review and meta-analysis
Farhat L, Reid M, Bloch M, Olfson E. Prevalence and gender distribution of excoriation (skin-picking) disorder: A systematic review and meta-analysis. Journal Of Psychiatric Research 2023, 161: 412-418. PMID: 37023597, PMCID: PMC11137851, DOI: 10.1016/j.jpsychires.2023.03.034.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsExcoriation disorderPublic health impactEpidemiological studiesGeneral populationSystematic reviewHealth impactsDifferent prevalence estimatesPooled prevalenceOverall prevalenceInclusion criteriaMale ratioPubMed searchPrevalence estimatesGender distributionDisordersPrevalenceDatabase searchEMBASEReviewPopulationPubMedPsycINFOStudyWomen
Academic Achievements & Community Involvement
Honors
honor Young Investigator Award
09/01/2024National AwardTourette Association of AmericaDetailsUnited Stateshonor Individual Biomedical Research Award
04/01/2023National AwardThe Hartwell FoundationDetailsUnited Stateshonor Michael Jenike Young Investigator Award
09/01/2022International AwardInternational OCD Foundation (IOCDF)DetailsUnited Stateshonor Scholar Award
07/01/2022Yale School of Medicine AwardYale Center for Clinical Investigation (YCCI)DetailsUnited Stateshonor Career Development Award
05/04/2022National AwardNational Institute of Mental Health (NIMH)DetailsUnited States
News
News
- February 07, 2025
2024-2025 YCSC postdoctoral scholar travel awardees announced
- November 15, 2024
Olfson receives young investigator award
- August 05, 2024
ADHD and DNA: Bedside-to-bench, International Study Sheds Light on Genetics
- June 10, 2024
Yale Child Study Center welcomes 2024 summer interns
Get In Touch
Contacts
Child Study Center
230 S Frontage Rd
New Haven, Connecticut 06519-1124
United States