2024
How Can I Maximize Patient Adherence to Therapy?
Tolomeo C. How Can I Maximize Patient Adherence to Therapy? 2024, 237-239. DOI: 10.1201/9781003523611-56.Peer-Reviewed Original Research
2022
Relationship between the use of nonpharmaceutical interventions and COVID-19 vaccination among U.S. child care providers: A prospective cohort study
Patel KM, Shafiq M, Malik AA, Cobanoglu A, Klotz M, Eric Humphries J, Lee A, Murray T, Wilkinson D, Yildirim I, Elharake JA, Diaz R, Rojas R, Kuperwajs Cohen A, Omer SB, Gilliam WS. Relationship between the use of nonpharmaceutical interventions and COVID-19 vaccination among U.S. child care providers: A prospective cohort study. Vaccine 2022, 40: 4098-4104. PMID: 35660329, PMCID: PMC9135692, DOI: 10.1016/j.vaccine.2022.05.064.Peer-Reviewed Original ResearchConceptsCOVID-19 vaccinationProspective cohort studyCare providersNonpharmaceutical interventionsChild care providersCohort studyLikelihood of vaccinationPreventative health behaviorsVaccinationHealth behaviorsCare programMandatory vaccinationSignificant associationVaccine mandatesDistrict of ColumbiaLarge healthInterventionPandemic controlCOVID-19Child care programsProvidersEmail surveyNonadherenceMeasuresMood Disorders in Transplantation: Bipolar Disorder Spectrum
Dahal R, Zimbrean P. Mood Disorders in Transplantation: Bipolar Disorder Spectrum. 2022, 13-22. DOI: 10.1007/978-3-031-15052-4_2.ChaptersBipolar disorderEnd-stage organ failureNeuropsychiatric adverse effectsRole of psychotropicsOrgan transplant recipientsSolid organ transplantationStandard immunosuppressantsPharmacological managementTransplant outcomesTransplant recipientsOrgan failureDisease burdenBipolar disorder spectrumSuccessful transplantationOrgan transplantationMood disordersGeneral populationTransplantationPatientsAdverse effectsDisorder spectrumDisordersPsychological effectsNonadherenceImmunosuppressants
2021
Novel Tool to Monitor Adherence to Oral Oncolytics: A Pilot Study.
Sun W, Reeve R, Ouellette T, Stutsky M, De Jesus R, Huffer MJ, Mougalian SS. Novel Tool to Monitor Adherence to Oral Oncolytics: A Pilot Study. JCO Clinical Cancer Informatics 2021, 5: 701-708. PMID: 34166064, DOI: 10.1200/cci.20.00151.Peer-Reviewed Original ResearchConceptsPilot studyCases of nonadherenceOral chemotherapy agentsCategory of patientsText message interventionMedication-taking behaviorCategory 2Category 3Category 1Cyclical regimenOral therapyOral oncolyticsCancer carePreintervention stageSuch therapyChemotherapy agentsAverage adherenceHigh riskPost interventionPatientsNonadherenceAdherencePrescription bottlesIntervention stageCapecitabineAtherosclerotic Cardiovascular Disease, Cancer, and Financial Toxicity Among Adults in the United States
Valero-Elizondo J, Chouairi F, Khera R, Grandhi GR, Saxena A, Warraich HJ, Virani SS, Desai NR, Sasangohar F, Krumholz HM, Esnaola NF, Nasir K. Atherosclerotic Cardiovascular Disease, Cancer, and Financial Toxicity Among Adults in the United States. JACC CardioOncology 2021, 3: 236-246. PMID: 34396329, PMCID: PMC8352280, DOI: 10.1016/j.jaccao.2021.02.006.Peer-Reviewed Original ResearchCost-related medication nonadherenceFinancial toxicityMedication nonadherenceNational Health Interview SurveyAtherosclerotic cardiovascular diseaseMedical billsHealth Interview SurveyCancer careASCVDCardiovascular diseaseHigh burdenHigher oddsElderly populationCancerInterview SurveyFood insecurityCareNonadherenceSignificant proportionAdultsToxicityHigh financial distressPatientsPrevalenceDiseaseLeveraging behavioral economics to promote treatment adherence: A primer for the practicing dermatologist
Woodbury MJ, Cohen JM, Merola JF, Perez-Chada LM. Leveraging behavioral economics to promote treatment adherence: A primer for the practicing dermatologist. Journal Of The American Academy Of Dermatology 2021, 87: 1075-1080. PMID: 34098000, DOI: 10.1016/j.jaad.2021.05.049.Peer-Reviewed Original ResearchConceptsTreatment adherenceSuboptimal clinical outcomesSuboptimal treatment adherenceQuality of lifeLifestyle modificationMedical therapyClinical outcomesDermatologic patientsPatient adherenceChronic diseasesEfficacious therapyEconomic burdenHealth behaviorsUnmet needScalable interventionsHealth policyAdherenceHealth carePatientsTherapyDiseaseNonadherencePsoriasisDearth of researchPubMed
2020
Intentional and unintentional nonadherence to hydroxyurea among people with sickle cell disease: a qualitative study
Hodges JR, Phillips SM, Norell S, Nwosu C, Khan H, Luo L, Badawy SM, King A, Tanabe P, Treadwell M, Rojas Smith L, Calhoun C, Hankins JS, Porter J. Intentional and unintentional nonadherence to hydroxyurea among people with sickle cell disease: a qualitative study. Blood Advances 2020, 4: 4463-4473. PMID: 32941646, PMCID: PMC7509876, DOI: 10.1182/bloodadvances.2020001701.Peer-Reviewed Original ResearchConceptsSickle cell diseaseSickle Cell Disease Implementation ConsortiumAdherence barriersCell diseaseMedication adherence barriersHealth care providersNonadherence factorsHydroxyurea therapyPatient adherenceUnintentional nonadherenceSCD populationCare providersEfficacious treatmentPatient choiceClinical discussionAge 15NonadherenceHydroxyureaDiseaseAdherenceQualitative studyParticipantsSemi-structured interviewsMedicationsRegimensAssociation Between Cost-Related Medication Nonadherence and Hypertension Management Among US Adults
Fang J, Chang T, Wang G, Loustalot F. Association Between Cost-Related Medication Nonadherence and Hypertension Management Among US Adults. American Journal Of Hypertension 2020, 33: 879-886. PMID: 32369108, DOI: 10.1093/ajh/hpaa072.Peer-Reviewed Original ResearchConceptsCurrent antihypertensive medication useCost-related medication nonadherenceAntihypertensive medication useNormal blood pressureSelf-reported hypertensionBlood pressureMedication useHypertension managementMedication nonadherenceUS adultsPrevalence ratiosSelf-reported antihypertensive medication useNational Health Interview SurveyAdjusted prevalence ratiosHealth Interview SurveyAdherence persistUncontrolled hypertensionAdjusted prevalenceHypertensionAdjusted percentageNonadherenceInterview SurveyMonthsFinancial barriersAdultsBurden and Consequences of Financial Hardship From Medical Bills Among Nonelderly Adults With Diabetes Mellitus in the United States
Caraballo C, Valero-Elizondo J, Khera R, Mahajan S, Grandhi GR, Virani SS, Mszar R, Krumholz HM, Nasir K. Burden and Consequences of Financial Hardship From Medical Bills Among Nonelderly Adults With Diabetes Mellitus in the United States. Circulation Cardiovascular Quality And Outcomes 2020, 13: e006139. PMID: 32069093, DOI: 10.1161/circoutcomes.119.006139.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsBlack or African AmericanComorbidityCost of IllnessCross-Sectional StudiesDiabetes MellitusFemaleFinancing, PersonalFood SupplyHealth Care CostsHealth Care SurveysHealth ExpendituresHealth Services AccessibilityHumansIncomeMaleMedically UninsuredMiddle AgedPatient ComplianceRisk AssessmentRisk FactorsUnited StatesYoung AdultConceptsDiabetes mellitusMedical billsHigher oddsMedical careNational Health Interview Survey dataHealth Interview Survey dataCost-related medication nonadherenceHigher comorbidity burdenCost-related nonadherenceSelf-reported diagnosisNon-Hispanic blacksInterview Survey dataFinancial hardshipMedication nonadherenceMean ageNonmedical needsHigh prevalenceMellitusMultivariate analysisPocket expenditureFood insecurityNonadherenceHigh financial distressPatientsAdults
2019
Cost‐Related Medication Nonadherence Among Older Adults: Findings From a Nationally Representative Sample
Chung GC, Marottoli RA, Cooney LM, Rhee TG. Cost‐Related Medication Nonadherence Among Older Adults: Findings From a Nationally Representative Sample. Journal Of The American Geriatrics Society 2019, 67: 2463-2473. PMID: 31437309, DOI: 10.1111/jgs.16141.Peer-Reviewed Original ResearchConceptsCost-related medication nonadherenceNational Health Interview SurveyMedication nonadherenceHealth Interview SurveyOlder adultsRisk factorsMultivariable logistic regression analysisInterview SurveyModifiable risk factorsLow-cost medicationsMedication therapy managementLogistic regression analysisChronic disease subgroupsLow socioeconomic levelCross-sectional analysisNationally Representative SampleFemale sexSubgroup analysisAlternative therapiesTherapy managementNonadherenceDisease subgroupsFunctional limitationsYounger agePrescription drugs
2017
Long‐term adherence with psychiatric treatment among patients with psychogenic nonepileptic seizures
Tolchin B, Dworetzky BA, Baslet G. Long‐term adherence with psychiatric treatment among patients with psychogenic nonepileptic seizures. Epilepsia 2017, 59: e18-e22. PMID: 29218816, DOI: 10.1111/epi.13969.Peer-Reviewed Original ResearchConceptsBrief Illness Perception QuestionnairePsychogenic nonepileptic seizuresLong-term adherencePsychiatric treatmentPrior diagnosisNonepileptic seizuresCox proportional hazards regression analysisProportional hazards regression analysisProspective cohort studyHazards regression analysisFirst outpatient visitIllness Perception QuestionnairePercent of subjectsLower scoresCohort studyPsychiatric visitsOutpatient visitsVisit 2Risk factorsFourth visitOne's illnessSurvival analysisNonadherencePerception QuestionnairePatients
2016
Patient-reported financial barriers to adherence to treatment in neurology
Moura L, Schwamm E, Moura V, Seitz M, Hoch D, Hsu J, Schwamm L. Patient-reported financial barriers to adherence to treatment in neurology. ClinicoEconomics And Outcomes Research 2016, 8: 685-694. PMID: 27895506, PMCID: PMC5117903, DOI: 10.2147/ceor.s119971.Peer-Reviewed Original ResearchMedication adherenceFinancial barriersPatient-reported failuresEffective medical therapyRoutine outpatient carePatient-reported dataCross-sectional surveyNeurology appointmentPatient characteristicsMedical therapyNeurology clinicMean agePrescription medicationsOutpatient careNeurological conditionsClinical informationNeurological diseasesNeurological disordersPatientsDemographic characteristicsAdherenceNonadherenceTherapyPreferred languageMedicationsTelemonitoring Adherence to Medications in Heart Failure Patients (TEAM-HF): A Pilot Randomized Clinical Trial
Gallagher BD, Moise N, Haerizadeh M, Ye S, Medina V, Kronish IM. Telemonitoring Adherence to Medications in Heart Failure Patients (TEAM-HF): A Pilot Randomized Clinical Trial. Journal Of Cardiac Failure 2016, 23: 345-349. PMID: 27818309, PMCID: PMC5380538, DOI: 10.1016/j.cardfail.2016.11.001.Peer-Reviewed Original ResearchConceptsHeart failurePercent of patientsHeart failure patientsEligible patientsGroup patientsFailure patientsMost patientsMedian ageMedication nonadherenceMedication adherenceTelephonic supportAdherence devicesAdherence monitoringPassive adherenceClinical trialsPatientsAdherenceNonadherenceFuture studiesDaysPercentReadmissionHospitalizationMedicationsTrialsPill Burden Influences the Association Between Time-Based Prospective Memory and Antiretroviral Therapy Adherence in Younger But Not Older HIV-Infected Adults
Sheppard D, Weber E, Casaletto K, Avci G, Woods S, Grant I, Atkinson J, Ellis R, McCutchan J, Marcotte T, Marquie-Beck J, Sherman M, Ellis R, McCutchan J, Letendre S, Capparelli E, Schrier R, Rosario D, Heaton R, Cherner M, Iudicello J, Moore D, Morgan E, Dawson M, Jernigan T, Fennema-Notestine C, Archibald S, Hesselink J, Annese J, Taylor M, Masliah E, Achim C, Everall I, Richman D, Smith D, McCutchan J, Achim C, Lipton S, Atkinson J, Gamst A, Cushman C, Abramson I, Vaida F, Deutsch R, Umlauf A. Pill Burden Influences the Association Between Time-Based Prospective Memory and Antiretroviral Therapy Adherence in Younger But Not Older HIV-Infected Adults. Journal Of The Association Of Nurses In AIDS Care 2016, 27: 595-607. PMID: 27160771, PMCID: PMC4976032, DOI: 10.1016/j.jana.2016.03.006.Peer-Reviewed Original ResearchConceptsLow pill burdenPill burdenYoung HIVMedication Event Monitoring SystemHigh pill burdenAntiretroviral therapy adherenceEvent Monitoring SystemARV adherenceOlder HIVAntiretroviral adherenceTherapy adherenceHIVOlder groupAdherenceSuboptimal useHigher likelihoodBurdenTime-based prospective memoryMeasures of PMAdultsAssociationNonadherenceFeasibility and success of cell-phone assisted remote observation of medication adherence (CAROMA) in clinical trials
DeWorsop D, Creatura G, Bluez G, Thurnauer H, Forselius-Bielen K, Ranganathan M, Deaso E, Bhat JA, D’Souza D. Feasibility and success of cell-phone assisted remote observation of medication adherence (CAROMA) in clinical trials. Drug And Alcohol Dependence 2016, 163: 24-30. PMID: 27068252, DOI: 10.1016/j.drugalcdep.2016.02.045.Peer-Reviewed Original ResearchConceptsMedication adherenceClinical trialsStudy medicationMedication nonadherenceDrug levelsActive study medicationWeekly study visitsPlacebo-controlled trialPlasma drug levelsSubstance abuse disordersPill countStudy visitStudy completionFace visitsClinical careAbuse disordersMedicationsCannabis dependencePilot studyTrialsAdherenceVisitsNonadherenceWeekly faceHigh rate
2015
Prescription drug insurance and cost-related medication nonadherence among Medicare seniors: findings from two national surveys
Jensen G, Xu X. Prescription drug insurance and cost-related medication nonadherence among Medicare seniors: findings from two national surveys. Journal Of Pharmaceutical Health Services Research 2015, 7: 11-21. DOI: 10.1111/jphs.12116.Peer-Reviewed Original ResearchCost-related nonadherenceMultiple chronic conditionsMedical Expenditure Panel SurveyChronic conditionsDrug insuranceMedicare seniorsCost-related medication nonadherenceChronic health conditionsMultivariable regression modelsPrescription drug insuranceMedication nonadherenceChronic illnessCardiovascular diseaseRepresentative data sourcesOlder adultsHealth conditionsMonthsLower likelihoodDevastating consequencesMedicationsNonadherenceLower ratesNational surveyRetirement StudyRegression modelsBarriers to HIV Medication Adherence: Examining Distinct Anxiety and Depression Symptoms among Women Living with HIV Who Experienced Childhood Sexual Abuse
Willie TC, Overstreet NM, Sullivan TP, Sikkema KJ, Hansen NB. Barriers to HIV Medication Adherence: Examining Distinct Anxiety and Depression Symptoms among Women Living with HIV Who Experienced Childhood Sexual Abuse. Behavioral Medicine 2015, 42: 120-127. PMID: 26010763, PMCID: PMC4710561, DOI: 10.1080/08964289.2015.1045823.Peer-Reviewed Original ResearchConceptsHIV medication nonadherenceMedication nonadherenceAntiretroviral medicationsMedication adherenceChildhood sexual abuseDepression symptomsHIV medication adherenceLogistic regression analysisMental health interventionsHIV medicationsSexual abuseRisk factorsHIVHealth interventionsSecondary analysisNonadherenceMedicationsSymptom componentsWomenDepressionDistinct anxietyAdherenceRegression analysisSymptomsAnxietyAre two commonly used self-report questionnaires useful for identifying antihypertensive medication nonadherence?
Gallagher BD, Muntner P, Moise N, Lin JJ, Kronish IM. Are two commonly used self-report questionnaires useful for identifying antihypertensive medication nonadherence? Journal Of Hypertension 2015, 33: 1108-1113. PMID: 25909704, PMCID: PMC4500106, DOI: 10.1097/hjh.0000000000000503.Peer-Reviewed Original ResearchConceptsVisual analog scaleAntihypertensive medication nonadherenceUncontrolled hypertensionSelf-report questionnairesMedication nonadherenceGold standardMorisky Medication Adherence ScaleAntihypertensive medication regimenMedication Adherence ScalePrimary care visitsLikelihood ratioAntihypertensive medicationsCare visitsMedication regimenMMAS-8Adherence ScaleAnalog scaleLow adherenceHigh adherenceElectronic pillboxNonadherenceHypertensionSecond visitClinical settingSRQ scores
2012
Pregestational Diabetes With Extreme Insulin Resistance
Zuckerwise LC, Werner EF, Pettker CM, McMahon-Brown EK, Thung SF, Han CS. Pregestational Diabetes With Extreme Insulin Resistance. Obstetrics And Gynecology 2012, 120: 439-442. PMID: 22825259, DOI: 10.1097/aog.0b013e31824fd27d.Peer-Reviewed Original ResearchConceptsSevere insulin resistanceInsulin resistanceGlycemic controlInsulin requirementsDiabetic patientsPregestational diabetes mellitusTreatment of patientsExtreme insulin resistancePregestational diabetesDiabetes mellitusRegular insulinPregnant womenPatientsHigh dosesInsulinPregnancyEffective alternativeWomenMellitusNonadherenceDiabetesDosesControl
2011
Co-occurring marijuana use is associated with medication nonadherence and nonplanning impulsivity in young adult heavy drinkers
Peters EN, Leeman RF, Fucito LM, Toll BA, Corbin WR, O'Malley SS. Co-occurring marijuana use is associated with medication nonadherence and nonplanning impulsivity in young adult heavy drinkers. Addictive Behaviors 2011, 37: 420-426. PMID: 22189052, PMCID: PMC3288288, DOI: 10.1016/j.addbeh.2011.11.036.Peer-Reviewed Original ResearchConceptsCo-occurring marijuana useAdult heavy drinkersYoung adult heavy drinkersHeavy drinkersMedication nonadherenceAlcohol consumptionHigh-risk clinical profileMarijuana useAlcohol-related negative consequencesUse of cigarettesAlcohol-induced disinhibitionBrief individual counselingClinical profileClinical trialsSelf-report assessmentsNonadherenceHeavy drinkingYoung adultsDemographic characteristicsDrinkersIndividual counselingClinical samplesHeavy alcoholMedicationsDrinking
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