2020
Alcohol- and speeding-related fatal crashes among novice drivers age 18–20 not fully licensed at the time of the crash
Romano E, Fell JC, Li K, Simons-Morton BG, Vaca FE. Alcohol- and speeding-related fatal crashes among novice drivers age 18–20 not fully licensed at the time of the crash. Drug And Alcohol Dependence 2020, 218: 108417. PMID: 33250377, PMCID: PMC8101556, DOI: 10.1016/j.drugalcdep.2020.108417.Peer-Reviewed Original ResearchConceptsFatality Analysis Reporting SystemAge 18Zip codesAlcohol useLower median household incomeFatal crashesLicense statusDriver licensing programsAlcohol-related fatal crashesMedian household incomeMean household incomeLogistic regressionTeen crash riskHousehold incomeGDL programsGDL restrictionsDriver's license statusReporting systemIndirect evidenceLicensing programsYoung driversNFLDPrevalenceIndividuals
2019
Systematic Review of Chronic Discrimination and Changes in Biology During Pregnancy Among African American Women
Chaney C, Lopez M, Wiley KS, Meyer C, Valeggia C. Systematic Review of Chronic Discrimination and Changes in Biology During Pregnancy Among African American Women. Journal Of Racial And Ethnic Health Disparities 2019, 6: 1208-1217. PMID: 31385262, DOI: 10.1007/s40615-019-00622-8.Peer-Reviewed Original ResearchConceptsChronic racial discriminationAfrican American womenSystematic reviewAmerican womenRacial health disparitiesInclusion criteriaMaternal biologyLarger sample sizeCardiovascular systemChronic discriminationHealth disparitiesHealth existLiterature searchPregnancyPsycINFO databasesRelevant biomarkersStudy designSmall sample sizeSample sizeEffective study designPreliminary evidenceCurrent literatureWomenIndirect evidenceInformative method
2017
Extending the Reach of Evidence-Based Medicine A Proposed Categorization of Lower-Level Evidence
Detterbeck FC, Gould MK, Lewis SZ, Patel S. Extending the Reach of Evidence-Based Medicine A Proposed Categorization of Lower-Level Evidence. CHEST Journal 2017, 153: 498-506. PMID: 28923759, DOI: 10.1016/j.chest.2017.09.006.Peer-Reviewed Original Research
2011
Variation in Genes Encoding the Neuroactive Steroid Synthetic Enzymes 5α‐Reductase Type 1 and 3α‐Reductase Type 2 Is Associated With Alcohol Dependence
Milivojevic V, Kranzler HR, Gelernter J, Burian L, Covault J. Variation in Genes Encoding the Neuroactive Steroid Synthetic Enzymes 5α‐Reductase Type 1 and 3α‐Reductase Type 2 Is Associated With Alcohol Dependence. Alcohol Clinical And Experimental Research 2011, 35: 946-952. PMID: 21323680, PMCID: PMC3083475, DOI: 10.1111/j.1530-0277.2010.01425.x.Peer-Reviewed Original ResearchMeSH Keywords3-Hydroxysteroid Dehydrogenases3-Oxo-5-alpha-Steroid 4-DehydrogenaseAdultAlcoholismAldo-Keto Reductase Family 1 Member C3Base SequenceCase-Control StudiesFemaleGenetic VariationHumansHydroxyprostaglandin DehydrogenasesMaleMembrane ProteinsMiddle AgedMolecular Sequence DataPolymorphism, Single NucleotideYoung AdultConceptsEndogenous neuroactive steroidsNeuroactive steroidsAlcohol dependenceAlcohol effectsType 2Minor alleleNon-Hispanic CaucasiansRatio of dihydrotestosteroneBladder cancerG alleleC alleleSteroid biosynthetic enzymesType 1Important mediatorKey mediatorSteroidsSingle nucleotide polymorphismsCase-control sampleHuman brainType IMarkersBiological phenotypesNucleotide polymorphismsIndirect evidenceMediators
2009
Behavioral assessment in patients with disorders of consciousness: gold standard or fool's gold?
Giacino JT, Schnakers C, Rodriguez-Moreno D, Kalmar K, Schiff N, Hirsch J. Behavioral assessment in patients with disorders of consciousness: gold standard or fool's gold? Progress In Brain Research 2009, 177: 33-48. PMID: 19818893, DOI: 10.1016/s0079-6123(09)17704-x.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessMedication side effectsSevere brain injuryAssessment of patientsBehavioral assessmentCurrent diagnostic criteriaFunctional neuroimaging findingsBrain injuryInvoluntary movementsNeuroimaging findingsMotor impairmentDiagnostic criteriaSide effectsBehavioral assessment techniquesNeurophysiologic markersVegetative stateConscious stateGold standardBehavioral assessment methodsFunctional neuroimagingPatientsDisordersIndirect evidenceBehavioral markersMarkers
1994
Relationship between maternal and neonatal levels of antibodies to 48 kDa SSB(La), 52 kDa SSA(Ro), and 60 kDa SSA(Ro) in pregnancies complicated by congenital heart block.
Buyon J, Waltuck J, Caldwell K, Crawford B, Slade S, Copel J, Chan E. Relationship between maternal and neonatal levels of antibodies to 48 kDa SSB(La), 52 kDa SSA(Ro), and 60 kDa SSA(Ro) in pregnancies complicated by congenital heart block. The Journal Of Rheumatology 1994, 21: 1943-50. PMID: 7837164.Peer-Reviewed Original ResearchConceptsCongenital heart blockAnti-60Heart blockCirculation of neonatesRatios of maternalUmbilical cord levelsTotal IgG levelsMean ratioAnti-52Neonatal circulationCord levelIgG levelsMaternal antibodiesSerum levelsNeonatal levelsUnaffected pregnanciesControl groupPregnancyFetal tissuesSelective depletionAntibodiesAutoantibodiesIndirect evidenceGroupNeonates
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