2024
Regulation and signaling of the LIM domain kinases
Casanova‐Sepúlveda G, Boggon T. Regulation and signaling of the LIM domain kinases. BioEssays 2024, 47: e2400184. PMID: 39361252, PMCID: PMC11663136, DOI: 10.1002/bies.202400184.Peer-Reviewed Original ResearchLIM domain kinaseDownstream of Rho GTPasesCofilin/actin depolymerizing factorActin cytoskeleton regulationIntra-molecular mechanismFilament severingDepolymerizing factorRho GTPasesActin depolymerizationCytoskeleton regulationRegulation mechanismKinaseLIMProteinRegulationGTPaseLIMK2LIMK1ActinEnzymeHuman healthSignalDepolymerizationCascadeMechanismCollective dynamics of actin and microtubule and its crosstalk mediated by FHDC1
San Tong C, Su M, Sun H, Le Chua X, Xiong D, Guo S, Raj R, Ong N, Lee A, Miao Y, Wu M. Collective dynamics of actin and microtubule and its crosstalk mediated by FHDC1. Frontiers In Cell And Developmental Biology 2024, 11: 1261117. PMID: 38567385, PMCID: PMC10985548, DOI: 10.3389/fcell.2023.1261117.Peer-Reviewed Original ResearchActin wavesActin polymerizationFormin-mediated actin polymerizationDynamics of actinMultiple cellular processesActin nucleationCell cortexCytoskeletal networkCellular processesMicrotubule networkCell divisionMicrotubule depolymerizationActinAntagonistic interplayMicrotubulesMolecular insightsProtein 1CellsCdc42Mast cellsConcurrent releaseDepolymerizationInteractionInhibition
2010
Catalytic C−O Bond Cleavage of 2-Aryloxy-1-arylethanols and Its Application to the Depolymerization of Lignin-Related Polymers
Nichols J, Bishop L, Bergman R, Ellman J. Catalytic C−O Bond Cleavage of 2-Aryloxy-1-arylethanols and Its Application to the Depolymerization of Lignin-Related Polymers. Journal Of The American Chemical Society 2010, 132: 16725-16725. DOI: 10.1021/ja109016b.Peer-Reviewed Original ResearchCatalytic C−O Bond Cleavage of 2-Aryloxy-1-arylethanols and Its Application to the Depolymerization of Lignin-Related Polymers
Nichols JM, Bishop LM, Bergman RG, Ellman JA. Catalytic C−O Bond Cleavage of 2-Aryloxy-1-arylethanols and Its Application to the Depolymerization of Lignin-Related Polymers. Journal Of The American Chemical Society 2010, 132: 12554-12555. PMID: 20731348, PMCID: PMC2943869, DOI: 10.1021/ja106101f.Peer-Reviewed Original ResearchConceptsBond cleavageEther cleavageO bond cleavageInitial mechanistic investigationsDepolymerization of ligninCorresponding monomerEthereal bondBond transformationCatalytic depolymerizationO activationMechanistic investigationsPolymersCleavageDepolymerizationMonomersRedoxBondsReagentsYieldReactionLigninProducts
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