2023
Synthesis of N‐Acylsulfenamides from (Hetero)Aryl Iodides and Boronic Acids by One‐Pot Sulfur‐Arylation and Dealkylation
Greenwood N, Cerny N, Deziel A, Ellman J. Synthesis of N‐Acylsulfenamides from (Hetero)Aryl Iodides and Boronic Acids by One‐Pot Sulfur‐Arylation and Dealkylation. Angewandte Chemie International Edition 2023, 63: e202315701. PMID: 38015869, PMCID: PMC10813656, DOI: 10.1002/anie.202315701.Peer-Reviewed Original ResearchS bond formationOne-pot approachBoronic acidsBond formationComplex bioactive compoundsComplex precursorSulfur functionalizationDiverse electrophilesSulfur groupsReaction conditionsDrug apixabanDrug precursorsS-substituentsThermal eliminationReaction inputConcerted eliminationMechanistic studiesBioactive compoundsSynthesisIodideBroad scopePrecursorsFunctionalizationCatalystAcidSynthesis of N‐Acylsulfenamides from (Hetero)Aryl Iodides and Boronic Acids by One‐Pot Sulfur‐Arylation and Dealkylation
Greenwood N, Cerny N, Deziel A, Ellman J. Synthesis of N‐Acylsulfenamides from (Hetero)Aryl Iodides and Boronic Acids by One‐Pot Sulfur‐Arylation and Dealkylation. Angewandte Chemie 2023, 136 DOI: 10.1002/ange.202315701.Peer-Reviewed Original ResearchOne-pot approachBoronic acidsBond formationComplex bioactive compoundsComplex precursorSulfur functionalizationDiverse electrophilesSulfur groupsReaction conditionsDrug apixabanDrug precursorsS-substituentsThermal eliminationReaction inputConcerted eliminationMechanistic studiesBioactive compoundsSynthesisIodideBroad scopePrecursorsFunctionalizationCatalystAcidStyreneBiological characterization of mulberry leaves bioconverted with Viscozyme L
Kim Y, Yu S, Kim K, Kim S, Park B, Oh H, Kim D, Park K, Ahn S. Biological characterization of mulberry leaves bioconverted with Viscozyme L. Molecular & Cellular Toxicology 2023, 19: 817-828. DOI: 10.1007/s13273-023-00350-5.Peer-Reviewed Original ResearchNormal phase silica gelNuclear magnetic resonance spectroscopyActive compoundsPotent α-glucosidase inhibitorsMagnetic resonance spectroscopyΑ-glucosidaseSilica gelΑ-glucosidase inhibitorsEthyl acetate extractionResonance spectroscopyColumn chromatographyCompoundsPH 4Biological activityEnhanced activityPharmaceutical productsCytotoxicity activityXanthine oxidase inhibitory activityBioactive compoundsAnti-diabetic effectsXanthine oxidaseAcetate extractionCaffeic acidAnti-oxidant propertiesInhibitory activity
2022
Role of quercetin and rutin in enhancing the therapeutic potential of mesenchymal stem cells for cold induced burn wound
Irfan F, Jameel F, Khan I, Aslam R, Faizi S, Salim A. Role of quercetin and rutin in enhancing the therapeutic potential of mesenchymal stem cells for cold induced burn wound. Regenerative Therapy 2022, 21: 225-238. PMID: 36092499, PMCID: PMC9420879, DOI: 10.1016/j.reth.2022.07.011.Peer-Reviewed Original ResearchMesenchymal stem cellsHUC-MSCsBurn woundsWound closureMore effective treatment optionsHuman umbilical cord mesenchymal stem cellsWound tissueUmbilical cord mesenchymal stem cellsTransplanted mesenchymal stem cellsEffective treatment optionDorsal rat skinRole of quercetinRegenerative potentialΜM of quercetinHuman umbilical cordAnti-oxidative propertiesWound healing mediatorsSpecific cell surface markersCell migrationCell surface markersStem cellsWound healing phasesDifferent time pointsHistological findingsBioactive compounds
2010
Not just passing through
Crawford JM, Clardy J. Not just passing through. Nature Chemistry 2010, 2: 805-807. PMID: 20861892, DOI: 10.1038/nchem.848.Peer-Reviewed Original Research
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