2024
Portable, low-field magnetic resonance imaging for evaluation of Alzheimer’s disease
Sorby-Adams A, Guo J, Laso P, Kirsch J, Zabinska J, Garcia Guarniz A, Schaefer P, Payabvash S, de Havenon A, Rosen M, Sheth K, Gomez-Isla T, Iglesias J, Kimberly W. Portable, low-field magnetic resonance imaging for evaluation of Alzheimer’s disease. Nature Communications 2024, 15: 10488. PMID: 39622805, PMCID: PMC11612292, DOI: 10.1038/s41467-024-54972-x.Peer-Reviewed Original ResearchConceptsWhite matter hyperintensitiesMachine learning pipelineMild cognitive impairmentAlzheimer's diseaseWhite matter hyperintensities volumeLearning pipelineAssessment of patientsIncrease accessCognitive impairmentEvaluation of Alzheimer's diseaseDementiaLF-MRIPoint-of-care assessmentMagnetic resonance imagingHippocampal volumeResonance imagingImage qualityDiseaseReduce costsAnisotropic counterpartIncreasing availabilityManual segmentationThrombosis risk with haemoglobin C trait and haemoglobin C disease: A systematic review
Jacobs J, Sharma D, Stephens L, Villalba C, Rinder H, Woo J, Wheeler A, Gerberi D, Goel R, Tormey C, Booth G, Bloch E, Adkins B. Thrombosis risk with haemoglobin C trait and haemoglobin C disease: A systematic review. British Journal Of Haematology 2024, 204: 1500-1506. PMID: 38291731, DOI: 10.1111/bjh.19313.Peer-Reviewed Original ResearchRisk of thrombosisHemoglobin C traitHemoglobin C diseaseVenous thromboembolismC diseaseIncreased risk of thrombosisProspective cohort studyFactor to thrombosisAssessment of patientsCohort studySystematic reviewInclusion criteriaPregnant individualsThrombotic riskCase seriesCase reportVTE riskChronic haemolysisSystematic literature reviewArterial thrombosisThrombosis riskHigh blood viscosityIncreased riskThrombosisC trait
2022
Real-world Practice Patterns and Safety of Concurrent Radiotherapy and Cabozantinib in Metastatic Renal Cell Carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium
Loo Gan C, Huang J, Pan E, Xie W, Schmidt A, Labaki C, Meza L, Bouchard G, Li H, Jackson-Spence F, Sánchez-Ruiz C, Powles T, Kumar S, Weise N, Hall W, Rose B, Beuselinck B, Suarez C, Pal S, Choueiri T, Heng D, McKay R. Real-world Practice Patterns and Safety of Concurrent Radiotherapy and Cabozantinib in Metastatic Renal Cell Carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium. European Urology Oncology 2022, 6: 204-211. PMID: 36328934, DOI: 10.1016/j.euo.2022.10.004.Peer-Reviewed Original ResearchConceptsMetastatic renal cell carcinomaMRCC treated with cabozantinibRenal cell carcinomaAdverse eventsRisk-benefit assessmentCell carcinomaReceiving radiotherapyInternational Metastatic Renal Cell Carcinoma Database ConsortiumPatients treated with stereotactic ablative body radiotherapyInternational multicenter retrospective studyStereotactic ablative body radiotherapyPractice patternsConventional palliative radiotherapyGrade 5 eventsIntermediate-risk diseaseReceipt of radiotherapyMultiple brain metastasesMetastatic kidney cancerRadiotherapy-related toxicityCourse of radiotherapyEfficacy of cabozantinibMulticenter retrospective studyStudy of patientsOptimize treatment outcomesAssessment of patientsAssessment of the Patients with an Acute Abdomen
Nassar A, Spain D, Davis K. Assessment of the Patients with an Acute Abdomen. 2022, 17-27. DOI: 10.1007/978-3-031-07881-1_2.Peer-Reviewed Original ResearchThe Quality of Telehealth-Delivered Palliative Care During the Initial COVID-19 Pandemic Surge (S530)
Soliman A, Akgün K, Coffee J, Kapo J, Morrison L, Blatt L, Schulman-Green D, Feder S. The Quality of Telehealth-Delivered Palliative Care During the Initial COVID-19 Pandemic Surge (S530). Journal Of Pain And Symptom Management 2022, 63: 921-922. PMCID: PMC9001042, DOI: 10.1016/j.jpainsymman.2022.02.153.Peer-Reviewed Original ResearchPC consultationDiscussion of goalsPalliative carePandemic surgeSerious illnessFamily understandingCOVID-19 pandemic surgeLarge hospitalsInitial pandemic surgeInpatient PC consultationsQuality of telehealthPercent of patientsPalliative care servicesPrimary cancer diagnosisAssessment of patientsEarly COVID-19 pandemicCOVID-19 infection ratesCOVID-19 ratesElectronic health recordsMedian timePC servicesMean ageInitial consultationInterdisciplinary carePatients
2020
Evaluating the Clinical Impact of Rapid Response Electroencephalography: The DECIDE Multicenter Prospective Observational Clinical Study.
Vespa PM, Olson DM, John S, Hobbs KS, Gururangan K, Nie K, Desai MJ, Markert M, Parvizi J, Bleck TP, Hirsch LJ, Westover MB. Evaluating the Clinical Impact of Rapid Response Electroencephalography: The DECIDE Multicenter Prospective Observational Clinical Study. Critical Care Medicine 2020, 48: 1249-1257. PMID: 32618687, PMCID: PMC7735649, DOI: 10.1097/ccm.0000000000004428.Peer-Reviewed Original ResearchConceptsNonconvulsive seizuresSeizure diagnosisTreatment planProspective observational clinical studyDiagnostic assessmentObservational clinical studyAssessment of patientsCritical care settingSerious adverse effectsTherapeutic decision makingProspective multicenterSecondary outcomesICU patientsPrimary outcomeStatus epilepticusHigh suspicionElectroencephalography assessmentAcademic hospitalBedside assessmentClinical impactClinical studiesObservational studyCare settingsPhysician confidencePatientsUsing patient-reported outcome measures for program evaluation: Design and findings on intention-to-treat outcomes from the Veterans Outcome Assessment survey
Katz IR, Resnick SG, Kasprow WJ, Boden MT, Cherkasova E, Fielstein EM, Trafton JA, Hoff RA. Using patient-reported outcome measures for program evaluation: Design and findings on intention-to-treat outcomes from the Veterans Outcome Assessment survey. Psychiatry Research 2020, 291: 113226. PMID: 32590230, DOI: 10.1016/j.psychres.2020.113226.Peer-Reviewed Original ResearchConceptsPatient-reported outcome measuresMeasurement-based careTreat outcomesOutcome measuresGeneral mental health clinicsOngoing mental health careVeterans Outcome Assessment surveyVeterans Health Administration patientsAssessment of patientsMental health clinicsMental health treatmentMental health careProgram evaluationOngoing treatmentHealth clinicsHealth treatmentPatientsHealth careCareOutcomesTreatmentAssessment surveyClinicEvaluationFindingsAssessment of Patient and Caregiver Attitudes and Approaches to Decision-Making Regarding Bone Marrow Transplant for Sickle Cell Disease
Bakshi N, Katoch D, Sinha C, Ross D, Quarmyne M, Loewenstein G, Krishnamurti L. Assessment of Patient and Caregiver Attitudes and Approaches to Decision-Making Regarding Bone Marrow Transplant for Sickle Cell Disease. JAMA Network Open 2020, 3: e206742. PMID: 32469414, PMCID: PMC7260617, DOI: 10.1001/jamanetworkopen.2020.6742.Peer-Reviewed Original ResearchConceptsBone marrow transplantCaregivers of patientsSickle cell diseasePatient decision aidMarrow transplantMedian ageCurative treatmentCell diseaseGroup 2Group 1Caregiver attitudesNovel disease-modifying therapiesDisease-modifying therapiesSickle cell clinicAssessment of patientsFuture prospective studiesRandomized clinical trialsParent trialProspective studyTreatment optionsClinical trialsNeeds assessment phaseMAIN OUTCOMECell clinicPatients32 Cardiac Imaging in Heart Failure
St. John Sutton M, Morrison A, Sinusas A, Ferrari V. 32 Cardiac Imaging in Heart Failure. 2020, 418-448.e5. DOI: 10.1016/b978-0-323-60987-6.00032-6.Peer-Reviewed Original ResearchCardiovascular magnetic resonanceHeart failureCardiac imagingCardiac resynchronization therapyManagement of patientsValvular heart diseaseAssessment of patientsNuclear medicine techniquesDetection of cardiomyopathyAssessment of metabolismAutonomic dysfunctionResynchronization therapyHeart diseaseCMR imagingThree-dimensional echoMedicine techniquesPatientsMolecular imagingImagingMagnetic resonanceStandard techniquesEchocardiographyCardiomyopathyFailureDysfunction
2019
Enfeeblement in Elders with Essential Tremor: Characterizing the Phenomenon and Its Role in Caregiver Burden
Cersonsky T, Diaz D, Kellner S, Hickman R, Zdrodowska M, Monin J, Louis E. Enfeeblement in Elders with Essential Tremor: Characterizing the Phenomenon and Its Role in Caregiver Burden. Tremor And Other Hyperkinetic Movements 2019, 9 DOI: 10.5334/tohm.461.Peer-Reviewed Original ResearchCaregiver burdenEssential tremorAssessment of patientsCommon movement disorderGreater tremor severityMore depressive symptomsCaregivers of individualsClinical correlatesFunctional impairmentMovement disordersGait disabilityCaregiver needsDepressive symptomsOverall healthTremor severityOlder ageGreater burdenCaregiversTremorBurdenCognitive difficultiesDisabilityScoresEldersIndividuals
2018
Assessment of Patient-Centered Approaches to Collect Sexual Orientation and Gender Identity Information in the Emergency Department
Haider A, Adler RR, Schneider E, Leitz T, Ranjit A, Ta C, Levine A, Harfouch O, Pelaez D, Kodadek L, Vail L, Snyder C, German D, Peterson S, Schuur JD, Lau BD. Assessment of Patient-Centered Approaches to Collect Sexual Orientation and Gender Identity Information in the Emergency Department. JAMA Network Open 2018, 1: e186506. PMID: 30646332, PMCID: PMC6324335, DOI: 10.1001/jamanetworkopen.2018.6506.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttitude of Health PersonnelCohort StudiesData CollectionEmergency Medical ServicesEmergency Service, HospitalFemaleGender IdentityHealth PersonnelHumansMaleMedical RecordsMiddle AgedPatient SatisfactionPatient-Centered CareProfessional-Patient RelationsSexual and Gender MinoritiesSexual BehaviorUnited StatesYoung AdultConceptsGender minority patientsIllness severityMinority patientsGender identity informationOptimal patient-centered approachAssessment of patientsHigh patient satisfactionEmergency department settingPatient satisfaction measuresPatient-centered approachPatient-centered methodStakeholder advisory boardCohort studyED visitsED physiciansEligible adultsMean ageEmergency departmentPatient preferencesPatient satisfactionDepartment settingIntervention periodMAIN OUTCOMEPatientsSGM patients
2017
Comparison of risk scoring systems for patients presenting with upper gastrointestinal bleeding: international multicentre prospective study
Stanley AJ, Laine L, Dalton HR, Ngu JH, Schultz M, Abazi R, Zakko L, Thornton S, Wilkinson K, Khor CJ, Murray IA, Laursen SB. Comparison of risk scoring systems for patients presenting with upper gastrointestinal bleeding: international multicentre prospective study. The BMJ 2017, 356: i6432. PMID: 28053181, PMCID: PMC5217768, DOI: 10.1136/bmj.i6432.Peer-Reviewed Original ResearchConceptsUpper gastrointestinal bleedingRockall scoreGastrointestinal bleedingInternational multicentre prospective studyAdmission Rockall scoreFull Rockall scoreGlasgow-Blatchford scoreHigh-risk patientsMulticentre prospective studyAssessment of patientsPNED scoreHospital stayBlatchford scoreDay mortalityConsecutive patientsRisk patientsComposite endpointEndoscopic treatmentProspective studyClinical endpointsClinical utilityLower riskPatientsLarge hospitalsBleedingOptimizing the Use of Outcome Measures in Chronic Inflammatory Demyelinating Polyneuropathy
Allen J, Gelinas D, Lewis R, Nowak R, Wolfe G. Optimizing the Use of Outcome Measures in Chronic Inflammatory Demyelinating Polyneuropathy. TouchREVIEWS In Neurology 2017, 13: 26. DOI: 10.17925/usn.2017.13.01.26.Peer-Reviewed Original ResearchChronic inflammatory demyelinating polyneuropathyOverall Disability Sum ScoreOverall Neuropathy Limitations ScaleInflammatory demyelinating polyneuropathyOutcome measuresDemyelinating polyneuropathyDisability scoresMedical Research Council sum scoreSum scoreTreatment (INCAT) disability scoreInflammatory Neuropathy CauseOverall Disability ScaleRoutine daily practiceAssessment of patientsQuality of lifeAspects of impairmentDisability outcomesSensory dysfunctionMartin VigorimeterGrip strengthInflammatory RaschDisability ScaleLimitation ScaleClinical trialsSensory impairment
2016
Utility of B-type natriuretic peptides in the assessment of patients with systemic sclerosis-associated pulmonary hypertension in the PHAROS registry.
Chung L, Fairchild RM, Furst DE, Li S, Alkassab F, Bolster MB, Csuka ME, Derk CT, Domsic RT, Fischer A, Frech TM, Gomberg-Maitland M, Gordon JK, Hinchcliff M, Hsu V, Hummers LK, Khanna D, Medsger TAJ, Molitor JA, Preston IR, Schiopu E, Shapiro L, Hant F, Silver R, Simms R, Varga J, Steen VD, Zamanian RT. Utility of B-type natriuretic peptides in the assessment of patients with systemic sclerosis-associated pulmonary hypertension in the PHAROS registry. Clinical And Experimental Rheumatology 2016, 35 Suppl 106: 106-113. PMID: 27908301.Peer-Reviewed Original ResearchConceptsB-type natriuretic peptideNT-proBNP levelsPg/mLSSc-PHNT-proBNPPulmonary hypertensionSSc patientsSystemic sclerosisNatriuretic peptideBaseline B-type natriuretic peptideMedian B-type natriuretic peptideSystemic sclerosis-associated pulmonary hypertensionMulticenter prospective cohortNT-proBNP groupNatriuretic peptide levelsRight ventricular dysfunctionPredictors of mortalityPulmonary arterial hypertensionPredictors of progressionAssessment of patientsBaseline creatinineSSc-PAHArterial hypertensionPAH patientsVentricular dysfunction
2015
Recognizing signs and symptoms of bipolar disorder.
Carbray JA, Iennaco JD. Recognizing signs and symptoms of bipolar disorder. The Journal Of Clinical Psychiatry 2015, 76: e1479. PMID: 26646046, DOI: 10.4088/jcp.14073gc1c.Peer-Reviewed Original ResearchConceptsAdvanced practice nursesBipolar disorderPractice nursesPsychiatric-mental health advanced practice nursePsychiatric-mental health nursesAssessment of patientsCare of patientsMental health nursesVariety of symptomsAppropriate rating scalesHealth nursesAppropriate treatmentDiagnostic criteriaSuicidal thoughtsPatientsRating ScaleSymptomsNursesCME activitiesDisordersSignsCareImportant role
2009
Behavioral assessment in patients with disorders of consciousness: gold standard or fool's gold?
Giacino JT, Schnakers C, Rodriguez-Moreno D, Kalmar K, Schiff N, Hirsch J. Behavioral assessment in patients with disorders of consciousness: gold standard or fool's gold? Progress In Brain Research 2009, 177: 33-48. PMID: 19818893, DOI: 10.1016/s0079-6123(09)17704-x.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessMedication side effectsSevere brain injuryAssessment of patientsBehavioral assessmentCurrent diagnostic criteriaFunctional neuroimaging findingsBrain injuryInvoluntary movementsNeuroimaging findingsMotor impairmentDiagnostic criteriaSide effectsBehavioral assessment techniquesNeurophysiologic markersVegetative stateConscious stateGold standardBehavioral assessment methodsFunctional neuroimagingPatientsDisordersIndirect evidenceBehavioral markersMarkers
2004
Diagnostic CT Scans: Assessment of Patient, Physician, and Radiologist Awareness of Radiation Dose and Possible Risks1
Lee CI, Haims AH, Monico EP, Brink JA, Forman HP. Diagnostic CT Scans: Assessment of Patient, Physician, and Radiologist Awareness of Radiation Dose and Possible Risks1. Radiology 2004, 231: 393-8. PMID: 15031431, DOI: 10.1148/radiol.2312030767.Peer-Reviewed Original ResearchConceptsED physiciansCT scanCancer riskRadiation doseChest radiographsMost ED physiciansPercent of patientsAbdominopelvic CT scansAssessment of patientsEmergency department physiciansU.S. academic medical centersAcademic medical centerFlank painAdult patientsRadiologist awarenessDepartment physiciansMedical CenterPatientsCT dosesPhysiciansLifetime cancer riskDoseScansRadiologistsRisk
2000
Surgical therapy for atypical symptoms of GERD: patient selection and preoperative evaluation.
Floch N. Surgical therapy for atypical symptoms of GERD: patient selection and preoperative evaluation. Journal Of Clinical Gastroenterology 2000, 30: s45-7. PMID: 10777173.Peer-Reviewed Original ResearchConceptsGastroesophageal reflux diseaseManifestations of gastroesophageal reflux diseaseExtraesophageal manifestations of gastroesophageal reflux diseaseExtraesophageal manifestationsSymptoms of gastroesophageal reflux diseasePreoperative assessment of patientsAtypical symptoms of gastroesophageal reflux diseaseMedical therapy failureNoncardiac chest painAssessment of patientsChest painSurgical therapyTherapy failurePreoperative evaluationMedical therapyPatient selectionAtypical symptomsPreoperative assessmentPH test resultsReflux diseasePatientsSurgeryMedication noncompliancePH testingTherapySelf-Help and Guided Self-Help Treatments for Bulimia Nervosa and Binge Eating Disorder
GRILO C. Self-Help and Guided Self-Help Treatments for Bulimia Nervosa and Binge Eating Disorder. Journal Of Psychiatric Practice 2000, 6: 18-26. PMID: 15990473, DOI: 10.1097/00131746-200001000-00003.Peer-Reviewed Original ResearchProspective assessment of primary rectal cancer response to preoperative radiation and chemotherapy using 18‐fluorodeoxyglucose positron emission tomography
Guillem J, Calle J, Akhurst T, Tickoo S, Ruo L, Minsky B, Gollub M, Klimstra D, Mazumdar M, Paty P, Macapinlac H, Yeung H, Saltz L, Finn R, Erdi Y, Humm J, Cohen A, Larson S. Prospective assessment of primary rectal cancer response to preoperative radiation and chemotherapy using 18‐fluorodeoxyglucose positron emission tomography. Diseases Of The Colon & Rectum 2000, 43: 18-24. PMID: 10813118, DOI: 10.1007/bf02237238.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinoma, MucinousAntimetabolites, AntineoplasticFluorodeoxyglucose F18FluorouracilGlycolysisHumansNeoadjuvant TherapyNeoplasm StagingPilot ProjectsPreoperative CareProspective StudiesRadiopharmaceuticalsRadiotherapy DosageRectal NeoplasmsRemission InductionTomography, Emission-ComputedTomography, X-Ray ComputedConceptsFluorine-18 fluorodeoxyglucose positron emission tomographyPositron emission tomography parametersFluorodeoxyglucose positron emission tomographyPositron emission tomographyPreoperative radiationEmission tomographyTomography parametersRectal cancerFluorine-18Preoperative assessment of patientsCompletion of radiationPrimary rectal cancerStandardized uptake valueSphincter-preserving rectal cancer surgeryRectal cancer surgeryFluorine-18-fluorodeoxyglucose positron-emission tomography imagesVisual response scoreFluorodeoxyglucose positron emission tomography imagingAssessment of patientsPositron emission tomography imagingTethered tumorsLesion glycolysisEmission tomography imagingTumor volumePreoperative strategy
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